Skip to content
SPIRE HANDBOOKSLAY THE SPIRE 2
BuildsCharactersCardsRelicsPotionsChallengesRunsGuides
Search/
Home/Cards/Toxic
Toxic artwork
Status

Toxic

Energy
1
Rarity
Status
Pool
Status
Target
None

Base card

At the end of your turn, if this is in your Hand, take 5 damage.
Exhaust

Timing and keywords

Exhaust
Removed until the end of combat.
Main branchLast updated 2026-11-02
Toxic (Status card)/images/cards/toxic.webpAt the end of your turn, if this is in your Hand, take 5 damage.

Added by these enemies

MyteNormal in Act 2 - Hive.
Sources

Last updated 2026-11-02.

  • Game reference data: main branch
SPIRE HANDBOOK

An independent Slay the Spire 2 strategy reference.

Game artwork and game data © Mega Crit. Extracted reference data and images via Spire Codex.

Build comparisonCombat decisionsUnusual buildsChallenge routesRecorded runsEnemiesEvents & AncientsGameplay guidesAchievements & badgesVersion changesOfficial game ↗