Characters
Starting decks, relics, unlocks and strategies for the five Slay the Spire 2 characters.
| Character | HP | Energy | Starting relic | Unlock |
|---|---|---|---|---|
| 75 | 3 | Cracked Core | Play a run with Necrobinder. | |
| 80 | 3 | Burning Blood | Available initially. | |
| 66 | 3 | Bound Phylactery | Play a run with Regent. | |
| 75 | 3 | Divine Right | Play a run with Silent. | |
| 70 | 3 | Ring of the Snake | Play a run with Ironclad. |
5 entries

The Defect
Separate Orb damage from attacks, keep the right Orb available for Evoke effects, and add draw and defense before collecting more expensive Powers.

The Ironclad
Use Burning Blood to recover between fights while developing Vulnerable, Strength or Exhaust effects that improve the cards already in the deck.

The Necrobinder
Use Osty as a persistent defensive resource, then decide whether the offered cards turn that protection into attacks, Doom executions or Soul-driven turns.

The Regent
Count Stars separately from Energy, and choose card rewards that let the deck pay for its useful turns rather than accumulating unplayable finishers.

The Silent
Build enough early damage and discard access before collecting Sly payoffs, then choose between attack chains and Poison according to the rewards.
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