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Letter Opener artwork
Relics

Letter Opener

Rarity
Uncommon Relic
Pool
Shared

Effect

Every time you play 3 Skills in a single turn, deal 5 damage to ALL enemies.
Used inSilent Sly and discard ↗
Main branchLast updated 2026-11-02
Letter Opener (relic)/images/relics/letter_opener.webpEvery time you play 3 Skills in a single turn, deal 5 damage to ALL enemies.

Decisions and interactions

Silent Sly and discardLetter Opener rewards repeated Skills; it does not make an attack-heavy sequence count as Skills.Double Sealed Throne and Particle WallLetter Opener deals five damage to every enemy after three Skills in a turn.Baalorlord’s five-card Defect runHis run history records Precise Scissors at Neow, Letter Opener on floor 21, Unceasing Top on floor 26 and Data Disk on floor 29.

Recorded examples

Baalorlord’s five-card Defect run artwork
Run study

Baalorlord’s five-card Defect run

An Ascension 1 victory with five upgraded cards, Orb damage and Swift draws. The recorded Fiddle differs from its current effect.

DefectRecorded runSmall deck
Sources

Last updated 2026-11-02.

  • Game reference data: main branch

Related references

Double Sealed Throne and Particle WallUnusual buildBaalorlord’s five-card Defect runRun studySilent Sly and discardStrategy using this card, relic or character

Strategies using this

All strategies ↗
Silent Sly and discard artwork
silent

Silent Sly and discard

Draw-and-discard cards turn Sly cards into free plays before the turn ends. Balance discard outlets, useful Sly targets and a damage payoff so cycling produces a str…

SlyDiscardDraw
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Game artwork and game data © Mega Crit. Extracted reference data and images via Spire Codex.

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